Our Scholars

Year Recruited: 2003
( 7 Scholars )

Scott Barolo, Ph.D.

Affiliation(s):
Cell and Developmental Biology
Research Interests

Our goal is to better understand the structure and function of signal-regulated transcriptional enhancers and their role in development. Using the Drosophila model system, we are employing biochemical, genetic, bioinformatic, evolutionary, and transgenic approaches to the study of these questions.

Jimo Borjigin, Ph.D.

Affiliation(s):
Molecular and Integrative Physiology
Research Interests

Research in the Borjign lab is focused on three areas: mechanisms of circadian rhythms;
neurobiology of the dying brain; brain-heart connection.

David Ferguson, M.D., Ph.D.

Affiliation(s):
Pathology
Research Interests

The Ferguson Laboratory is interested in understanding how DNA repair in mammals works, and what roles it plays in cancer, immunity, and overall development. DNA damage occurs in many forms and numerous DNA repair complexes and pathways have evolved to combat them.

Anuj Kumar, Ph.D.

Affiliation(s):
Life Sciences Institute, Molecular, Cellular and Developmental Biology
Research Interests

The Kumar Lab utilizes functional genomics, proteomics, and bioinformatics to probe central signaling pathways underlying eukaryotic cell growth and function. In particular, we are currently studying a fundamental process wherein yeast cells undergo a dramatic change from a unicellular to a filamentous growth form. This growth transition is a critical determinant of fungal pathogenicity and also provides an excellent model regulatory network with relevance to ERK/MAPK signaling.

Daniel Michele, Ph.D.

Affiliation(s):
Internal MedicineMMG, Molecular and Integrative Physiology
Research Interests

The Michele laboratory is interested in the molecular mechanisms of human diseases of skeletal and cardiac muscle. By studying  molecular mechanisms of relatively rare genetic disorders such as muscular dystrophy, we hope to shed light important mechanisms required for the normal function of the heart and muscle, as well as identify new targets for therapy in muscular dystrophy and other heart and muscle diseases.

JoAnn Sekiguchi, Ph.D.

Affiliation(s):
Human Genetics, Internal MedicineMMG
Research Interests

Our lab studies mechanisms of DNA repair and how aberrant repair processes affect genomic stability, predisposition to cancer and immune system development. The projects in the lab are focused on characterizing the non-homologous end-joining (NHEJ) pathway of DNA double strand break repair, one of the two major pathways of double strand break repair in mammalian cells.

Billy Tsai, Ph.D.

Affiliation(s):
Cell and Developmental Biology
Research Interests

We use biochemical and cell biological approaches to understand the nature of interaction between different toxins and viruses with their host cell. Specifically, we are studying how cholera toxin and polyoma/SV40 virus hijack cellular machineries to cause disease.